Pediatric Protocol
The World Health Organization now estimates an annual incidence of just over one million pediatric TB cases worldwide. Despite significant advances in TB diagnostics in the last decade, these advances have not critically impacted pediatric TB. The true disease burden is difficult to ascertain as most children with TB are never diagnosed by standard microbiological methods. As a result, under-diagnosis of children with TB is common, specifically in high-burden settings, leading to high childhood mortality, specifically among children < 5 years of age. Moreover, pediatric TB is often only recognized post-mortem.
Note
Under FEND-TB 2, only repository samples are available for diagnostic purposes. No new prospective data collection will be conducted. The repository samples are available for the evaluation of your diagnostic. Please submit an application at the link below.
The FEND Pediatric program enrolled children under 5 years of age from sites in Peru and Uganda. Specimen types collected include: Stool, Upper airway swabs, Saliva, NPA/Nasal swabs, Urine, and Blood.