Feasibility of Novel Diagnostics for TB

in Endemic Countries

Analytic core lab rutgers

Moldova

peru

Mission

To support the evaluation of early-stage TB diagnostics & novel diagnostic strategies in the context of existing clinical algorithms in TB endemic countries.

FEND for TB will perform proof-of-principle studies of novel diagnostics & strategies and provide feedback to diagnostic developers on the performance of the technologies and their most effective use in endemic settings.

About

The primary purpose of the FEND for TB Consortium is to evaluate early stage diagnostics and novel diagnostic strategies for tuberculosis in the context of existing clinical algorithms in TB endemic countries.

 

fendtech@njms.rutgers.edu

Protocols

The Feasibility of Novel Diagnostics for TB in Endemic Countries (FEND for TB) Consortium, funded by the U.S. National Institutes of Health, is comprised of a group of international clinical and laboratory investigators with the primary purpose of supporting the evaluation of early-stage tuberculosis diagnostic assays and strategies in the context of existing clinical algorithms in tuberculosis endemic countries.

Samples

FEND-TB 2 is collecting prospective samples from adult index TB cases in Peru and from drug-resistant index cases in Moldova. In addition, a large repository of samples from FEND-TB 1 is available, which includes adult, pediatric, and drug-resistant cases.

Prospective Sample Collection

Adult Protocol
Peru

Drug Resistant Protocol
Moldova

Repository Samples Available

Adult Protocol
Peru, South Africa, Uganda, Vietnam

Pediatric Protocol
Peru, Uganda

Drug Resistant Protocol
Moldova, South Africa, Vietnam

For Manufacturers

FEND mission is to support the evaluation of early-stage TB diagnostics & novel diagnostic strategies in the context of existing clinical algorithms in TB endemic countries.

FEND for TB will perform proof-of-principle studies of novel diagnostics & strategies and provide feedback to diagnostic developers on the performance of the technologies and their most effective use in endemic settings.

Applications for TB diagnostics are now being accepted from August 30 to November 30, 2025. Applications may be reviewed on a rolling basis.

Support

Research on this website (FEND-TB.org) was supported by the U.S. National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) under Award Number U01AI152084. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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